Folate Receptor References
Scientific papers related to folate receptor
Folate Receptor-Positive Gynecological Cancer Cells: In Vitro and In Vivo Characterization
Pharmaceuticals
Published: 15 August 2017
Abstract
Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies
Oncotarget, 2018, Vol. 9, (No. 4), pp: 4485-4495
Published: December 15, 2017
Abstract
A number of folate receptor (FR) targeted small molecular drugs and monoclonal antibodies have been introduced into clinical trials to treat FR positive cancers. Because the therapeutic efficacy of these drugs depends prominently on the level of FR-α expression on the cancer cells,….
Tumour suppressor gene methylation and cervical cell folate concentration are determinants of high-risk human papillomavirus persistence: a nested case control study
Flatley et ai. BMC Cancer 2014, 14:803
Abstract
Background: Persistent infection with one or more high-risk human papillomavirus [HR-HPV] types increases the risk of intraepithelial neoplasia and cervical cancer. A nested case-control study was conducted to investigate the importance of cervical cell folate concentration and tumour….
Targeting folate receptor alpha for cancer treatment
Oncotarget. 2016 Aug 9; 7(32): 52553–52574.
Published online 2016 May 27. doi: 10.18632/oncotarget.9651
Abstract
Promising targeted treatments and immunotherapy strategies in oncology and advancements in our understanding of molecular pathways that underpin cancer development have reignited interest in the tumor-associated antigen Folate Receptor alpha (FRα)…
Folate receptors and transporters: biological role and diagnostic/therapeutic targets in cancer and other diseases
Journal of Experimental & Clinical Cancer Research volume 38, Article number: 125 (2019)
Published: 12 March 2019
Abstract
Folate receptors and transporters and one-carbon metabolism continue to be important areas of study given their essential roles in an assortment of diseases and as targets for treatment of cancer and inflammation….
Targeting the folate receptor for the treatment of ovarian cancer
TRANSLATIONAL CANCER RESEARCH
Vol 4, No 1 (February 2015)
Abstract
While conventional therapies have improved the outcome for patients with ovarian cancer, the disease still accounts for the most gynecological cancer-related deaths. The development of new treatment options is needed and efforts have focused on targeted therapies which aim to improve patient outcome by increasing anti-tumor activity while minimizing toxicity. The frequent overexpression of folate receptor α (FRα)…
Advances in targeting the folate receptor in the treatment/imaging of cancers
Chemical Science
Issue 4, 2018
Abstract
Expression of Folate Receptor Type α in Relation to Cell Type, Malignancy, and Differentiation in Ovary, Uterus, and Cervix
AACR Publications
Published September 1999
Abstract
Folate Receptor Alpha as a Therapeutic Target for Ovarian Cancer
OncLive
Published: Friday, April 19, 2019
